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Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE): Determining Therapeutic Goals for Treat-to-Target

The American Journal of Gastroenterology · 2015 · Vol. 110(9) · pp. 1324–1338

Laurent Peyrin‐Biroulet(Université de Lorraine)William J. Sandborn(Sands)Bruce E. Sands(New Leaders)Walter Reinisch(McMaster University)Willem A. Bemelman(Sands)Robert V. Bryant(Open Targets)Geert D’Haens(Academic Medical Center)Iris Dotan(Tel Aviv Sourasky Medical Center)Marla C. Dubinsky(Open Targets)Brian G. Feagan(Open Targets)Gionata Fiorino(IRCCS Humanitas Research Hospital)Richard B. Gearry(New Leaders)Suneeta Krishnareddy(New Leaders)Péter L. Lakatos(Open Targets)Edward V. Loftus(Open Targets)Philippe Marteau(Hôpital Lariboisière)Pia Munkholm(Zealand University Hospital)Travis B. Murdoch(Open Targets)Íngrid Ordás(Open Targets)Remo Panaccione(University of Calgary)Robert H. Riddell(Mount Sinai Hospital)Joannie Ruel(Open Targets)David T. Rubin(New Leaders)Mark Samaan(Sands)Corey A. Siegel(Open Targets)Mark S. Silverberg(University of Toronto)Jaap Stoker(Sands)S Schreiber(Open Targets)Simon Travis(Open Targets)Gert Van Assche(KU Leuven)Silvio Danese(IRCCS Humanitas Research Hospital)Julián Panés(New Leaders)Guillaume Bouguen(Sands)Sarah O’Donnell(University of Toronto)Benjamin Pariente(Hôpital Claude Huriez)Shawn Winer(New Leaders)Stephen B. Hanauer(Sands)Jean‐Frédéric Colombel✉(Icahn School of Medicine at Mount Sinai)

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Abstract

Evidence- and consensus-based recommendations for selecting the goals for treat-to-target strategies in patients with IBD are made available. Prospective studies are needed to determine how these targets will change disease course and patients' quality of life.

Inflammatory Bowel Disease Pregnancy and Medication Impact Microscopic ColitisMedicineInflammatory bowel diseaseSTRIDEIntensive care medicineDiseaseTherapeutic approachPhysical medicine and rehabilitationInternal medicine