reviewTop 1% cited

Anti-Mullerian hormone: a new marker for ovarian function

Reproduction · 2005 · Vol. 131(1) · pp. 1–9

Jenny A. Visser✉Frank H. de JongJoop S.E. Laven(Erasmus MC)Axel P. N. Themmen

Abstract

Anti-Müllerian hormone (AMH) is a member of the transforming growth factor beta family of growth and differentiation factors. In the ovary, AMH has an inhibitory effect on primordial follicle recruitment as well as on the responsiveness of growing follicles to follicle-stimulating hormone (FSH). The ovary-specific expression pattern in granulosa cells of growing nonselected follicles makes AMH an ideal marker for the size of the ovarian follicle pool. This review summarizes recent findings concerning AMH and its role as a marker for the quantitative aspect of ovarian reserve as well as ovarian dysfunction.

Reproductive Biology and Fertility Ovarian function and disorders Ovarian cancer diagnosis and treatmentAnti-Müllerian hormoneOvarian reserveOvaryFolliculogenesisFollicleOvarian follicleHormoneBiologyEndocrinologyInternal medicine

MeSH terms

AgingFemaleFertilityFollicle Stimulating HormoneGlycoproteinsHumansOvarian DiseasesOvaryTesticular HormonesBiomarkersPremenopauseAnti-Mullerian Hormone

Citations

796

FWCI

27.23

field-weighted impact

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100%

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Cited by

Consensus on women’s health aspects of polycystic ovary syndrome (PCOS): the Amsterdam ESHRE/ASRM-Sponsored 3rd PCOS Consensus Workshop Group