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Clinical Efficacy of an Automated High-Sensitivity C-Reactive Protein Assay

Clinical Chemistry · 1999 · Vol. 45(12) · pp. 2136–2141

Nader Rifai✉(Harvard University)Russell P. Tracy(University of Vermont)Paul M. Ridker(Brigham and Women's Hospital)

Abstract

Our findings indicate that the Latex method is equally as efficacious as the validated ELISA in classifying patients into cutoff points established by prospective studies for risk stratification for coronary and cerebrovascular disease.

Adipokines, Inflammation, and Metabolic Diseases Lipoproteins and Cardiovascular Health Blood properties and coagulationQuartileInterquartile rangeMedicineConfidence intervalC-reactive proteinAsymptomaticInternal medicineProspective cohort studyGastroenterologyRelative risk

MeSH terms

AgedAged, 80 and overAntioxidantsAspirinC-Reactive ProteinDouble-Blind MethodEnzyme-Linked Immunosorbent AssayHumansImmunoassayLatexMaleMiddle AgedMyocardial InfarctionPlatelet Aggregation InhibitorsProspective Studies

Citations

615

FWCI

17.73

field-weighted impact

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100%

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Inflammation and Atherosclerosis