article Open AccessTop 1% cited

A sensory neuron–expressed IL-31 receptor mediates T helper cell–dependent itch: Involvement of TRPV1 and TRPA1

Journal of Allergy and Clinical Immunology · 2013 · Vol. 133(2) · pp. 448–460.e7

Ferda Cevikbas✉(Düsseldorf University Hospital)Xidao Wang(University of California, San Francisco)Tasuku Akiyama(University of California, Davis)Cordula Kempkes(University of California, San Francisco)Terhi Savinko(Finnish Institute of Occupational Health)A.S. Antal(Heinrich Heine University Düsseldorf)Gabriela Kukova(Düsseldorf University Hospital)Timo Buhl(University of California, San Francisco)Akihiko Ikoma(University of California, San Francisco)Joerg Buddenkotte(University Hospital Münster)Vassili Soumelis(Institut Curie)M Feld(Düsseldorf University Hospital)Harri Alenius(Finnish Institute of Occupational Health)Stacey R. Dillon(Bristol-Myers Squibb (Germany))Earl Carstens(University of California, Davis)Bernhard Homey(Düsseldorf University Hospital)Allan I. Basbaum(University of California, San Francisco)Martin Steinhoff(University of California, San Francisco)

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Dermatology and Skin Diseases Herbal Medicine Research Studies Exercise and Physiological ResponsesTRPV1Transient receptor potential channelReceptorBiologyDorsal root ganglionIn vivoImmunologyCell biologyMedicineNeuroscience

MeSH terms

TRPA1 Cation ChannelAnimalsCells, CulturedFemaleGanglia, SpinalHumansInterleukinsMice, Inbred C57BLNerve Tissue ProteinsPruritusSensory Receptor CellsSkinCalcium ChannelsReceptors, InterleukinMice, Knockout

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Interleukins (from IL-1 to IL-38), interferons, transforming growth factor β, and TNF-α: Receptors, functions, and roles in diseases