articleTop 1% cited

A Comparison of Vancomycin and Metronidazole for the Treatment of Clostridium difficile-Associated Diarrhea, Stratified by Disease Severity

Clinical Infectious Diseases · 2007 · Vol. 45(3) · pp. 302–307

Fred A. Zar✉(University of Illinois Chicago)S. R. Bakkanagari(Saint Francis Hospital)K. M. L. S. T. Moorthi(Saint Francis Hospital)Melinda B. Davis(University of Illinois Chicago)

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Abstract

Our findings suggest that metronidazole and vancomycin are equally effective for the treatment of mild CDAD, but vancomycin is superior for treating patients with severe CDAD.

Clostridium difficile and Clostridium perfringens research Microscopic Colitis Helicobacter pylori-related gastroenterology studiesMetronidazoleMedicineVancomycinClostridium difficilePlaceboInternal medicineDiarrheaSurgeryClinical trialGastroenterology

MeSH terms

Administration, OralAdultAgedAnti-Infective AgentsDouble-Blind MethodEnterocolitis, PseudomembranousFemaleHumansMaleMetronidazoleMiddle AgedProspective StudiesSeverity of Illness IndexVancomycinClostridioides difficile

Citations

1,248

FWCI

34.36

field-weighted impact

References

Percentile

100%

vs. same field & year

Citations per year

Cited by

Clinical Practice Guidelines for Clostridium difficile Infection in Adults and Children: 2017 Update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA)