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Early Palliative Care for Patients with Metastatic Non–Small-Cell Lung Cancer

New England Journal of Medicine · 2010 · Vol. 363(8) · pp. 733–742

Jennifer S. Temel✉(Massachusetts General Hospital)Joseph A. Greer(Massachusetts General Hospital)Alona Muzikansky(Massachusetts General Hospital)Emily R. Gallagher(Massachusetts General Hospital)Sonal Admane(University at Buffalo, State University of New York)Vicki A. Jackson(Massachusetts General Hospital)Constance Dahlin(Massachusetts General Hospital)Craig D. Blinderman(Columbia University Irving Medical Center)Juliet Jacobsen(Massachusetts General Hospital)William F. Pirl(Massachusetts General Hospital)J. Andrew Billings(Massachusetts General Hospital)Thomas J. Lynch(Yale University)

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Abstract

Among patients with metastatic non-small-cell lung cancer, early palliative care led to significant improvements in both quality of life and mood. As compared with patients receiving standard care, patients receiving early palliative care had less aggressive care at the end of life but longer survival. (Funded by an American Society of Clinical Oncology Career Development Award and philanthropic gifts; ClinicalTrials.gov number, NCT01038271.)

Palliative Care and End-of-Life Issues Cancer survivorship and care Childhood Cancer Survivors' Quality of LifeMedicinePalliative careAmbulatory careDiseaseAmbulatoryLung cancerCancerEnd-of-life careIntensive care medicineOncology

MeSH terms

AffectAgedCarcinoma, Non-Small-Cell LungDepressionFemaleHumansLung NeoplasmsMaleMiddle AgedPalliative CareQuality of LifeTerminal CareTime FactorsLinear ModelsKaplan-Meier Estimate

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Association of Depression and Anxiety on Quality of Life, Treatment Adherence, and Prognosis in Patients with Advanced Non-small Cell Lung Cancer