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COLOR III: a multicentre randomised clinical trial comparing transanal TME versus laparoscopic TME for mid and low rectal cancer
Surgical Endoscopy · 2015 · Vol. 30(8) · pp. 3210–3215
Charlotte L. Deijen✉(Amsterdam UMC Location VUmc)Simone Velthuis(Ziekenhuis Gelderse Vallei)Alice Tsai(Imperial College London)Stella Mavroveli(Imperial College London)Elly S.M. de Lange–de Klerk(Amsterdam UMC Location VUmc)Colin Sietses(Ziekenhuis Gelderse Vallei)Jurriaan B. Tuynman(Amsterdam UMC Location VUmc)Antonio M. Lacy(Hospital Clínic de Barcelona)George B. Hanna(Imperial College London)H. Jaap Bonjer(Amsterdam UMC Location VUmc)
Abstract
The difference in involvement of CRM between the two treatment strategies is thought to be in favour of the TaTME. TaTME is therefore expected to be superior to laparoscopic TME in terms of oncological outcomes in case of mid and low rectal carcinomas.
Colorectal Cancer Surgical TreatmentsColorectal Cancer Screening and DetectionColorectal and Anal CarcinomasMedicineTotal mesorectal excisionColorectal cancerMesorectumClinical endpointSurgeryRandomized controlled trialQuality of life (healthcare)Laparoscopic surgeryLaparoscopy
MeSH terms
Transanal Endoscopic SurgeryMargins of ExcisionAnal CanalCarcinomaHumansMesenteryNeoplasm Recurrence, LocalLaparoscopyQuality of LifeRectal NeoplasmsRectumDigestive System Surgical ProceduresSurvival RateDisease-Free SurvivalOrgan Sparing Treatments
Funding
- Covidien
Citations
379
FWCI
15.23
field-weighted impact
References
31
Percentile
99%
vs. same field & year
Citations per year
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Circumferential Margin Involvement Is Still an Important Predictor of Local Recurrence in Rectal Carcinoma
The American Journal of Surgical Pathology · 2002 · 740 citations
Transanal natural orifice transluminal endoscopic surgery (NOTES) rectal resection: “down-to-up” total mesorectal excision (TME)—short-term outcomes in the first 20 cases
Surgical Endoscopy · 2013 · 299 citations
The mesorectum in rectal cancer surgery—the clue to pelvic recurrence?
British journal of surgery · 1982 · 2,894 citations
Laparoscopic versus open surgery for rectal cancer (COLOR II): short-term outcomes of a randomised, phase 3 trial
The Lancet Oncology · 2013 · 1,680 citations
Early colon cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
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Survival after laparoscopic surgery versus open surgery for colon cancer: long-term outcome of a randomised clinical trial
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