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Rapid Detection of Carbapenemase-producing <i>Enterobacteriaceae</i>
Emerging infectious diseases · 2012 · Vol. 18(9) · pp. 1503–1507
Patrice Nordmann✉(Bicêtre Hospital)Laurent Poirel(Université Paris-Sud)Laurent Dortet(Bicêtre Hospital)
Abstract
To rapidly identify carbapenemase producers in Enterobacteriaceae, we developed the Carba NP test. The test uses isolated bacterial colonies and is based on in vitro hydrolysis of a carbapenem, imipenem. It was 100% sensitive and specific compared with molecular-based techniques. This rapid (<2 hours), inexpensive technique may be implemented in any laboratory.
Antibiotic Resistance in BacteriaEnterobacteriaceae and Cronobacter ResearchPharmaceutical and Antibiotic Environmental ImpactsEnterobacteriaceaeImipenemMicrobiologyCarbapenemCarbapenem-resistant enterobacteriaceaeBiologyEnterobacteriaceae InfectionsAntibioticsEscherichia coliAntibiotic resistance
MeSH terms
Anti-Bacterial AgentsBacterial ProteinsBacteriological Techniquesbeta-LactamasesEnterobacteriaceaeEnterobacteriaceae InfectionsHumansHydrolysisSensitivity and SpecificityCarbapenems
Citations
752
FWCI
21.95
field-weighted impact
References
14
Percentile
100%
vs. same field & year
Citations per year
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References
Global Spread of Carbapenemase-producing<i>Enterobacteriaceae</i>
Emerging infectious diseases · 2011 · 2,276 citations
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