article Open AccessTop 1% cited
Cell Shape, Cytoskeletal Tension, and RhoA Regulate Stem Cell Lineage Commitment
Developmental Cell · 2004 · Vol. 6(4) · pp. 483–495
Rowena McBeath(Johns Hopkins University)Dana M. Pirone(Johns Hopkins University)Celeste M. Nelson(Johns Hopkins University)Kiran Bhadriraju(Johns Hopkins University)Christopher S. Chen✉(Johns Hopkins University)
Cellular Mechanics and InteractionsHippo pathway signaling and YAP/TAZMuscle Physiology and DisordersRHOACell biologyBiologyMesenchymal stem cellCytoskeletonCell fate determinationStem cellAdipogenesisCellular differentiationCell
MeSH terms
Cell CommunicationCell CountCell DifferentiationCells, CulturedCytoskeletonHumansMesodermActin CytoskeletonMutationMyosinsOsteoblastsOsteogenesisStem CellsStress, MechanicalProtein Serine-Threonine Kinases
Funding
- Georgetown University
- Whitaker Foundation
- National Institutes of Health
- National Institute of General Medical Sciences
- National Institute of Biomedical Imaging and Bioengineering
Citations
4,143
FWCI
31.85
field-weighted impact
References
56
Percentile
100%
vs. same field & year
Citations per year
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References
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Force and focal adhesion assembly: a close relationship studied using elastic micropatterned substrates
Nature Cell Biology · 2001 · 2,119 citations
Control of Cyclin D1, p27<sup>Kip1</sup>, and Cell Cycle Progression in Human Capillary Endothelial Cells by Cell Shape and Cytoskeletal Tension
Molecular Biology of the Cell · 1998 · 485 citations
Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton
The EMBO Journal · 1999 · 1,554 citations
Focal Contacts as Mechanosensors
The Journal of Cell Biology · 2001 · 1,416 citations
Rho-stimulated contractility drives the formation of stress fibers and focal adhesions.
The Journal of Cell Biology · 1996 · 1,664 citations
Pharmacological Properties of Y-27632, a Specific Inhibitor of Rho-Associated Kinases
Molecular Pharmacology · 2000 · 928 citations
Multilineage Potential of Adult Human Mesenchymal Stem Cells
Science · 1999 · 20,977 citations
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