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Cell Shape, Cytoskeletal Tension, and RhoA Regulate Stem Cell Lineage Commitment

Developmental Cell · 2004 · Vol. 6(4) · pp. 483–495
Rowena McBeathDana M. PironeCeleste M. NelsonKiran BhadrirajuChristopher S. Chen
Cellular Mechanics and InteractionsHippo pathway signaling and YAP/TAZMuscle Physiology and DisordersRHOACell biologyBiologyMesenchymal stem cellCytoskeletonCell fate determinationStem cellAdipogenesisCellular differentiationCell

MeSH terms

Cell CommunicationCell CountCell DifferentiationCells, CulturedCytoskeletonHumansMesodermActin CytoskeletonMutationMyosinsOsteoblastsOsteogenesisStem CellsStress, MechanicalProtein Serine-Threonine Kinases

Funding

  • Georgetown University
  • Whitaker Foundation
  • National Institutes of Health
  • National Institute of General Medical Sciences
  • National Institute of Biomedical Imaging and Bioengineering
Citations
4,143
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