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Late-life depression and risk of vascular dementia and Alzheimer's disease: systematic review and meta-analysis of community-based cohort studies
The British Journal of Psychiatry · 2013 · Vol. 202(5) · pp. 329–335
Breno S. Diniz(University of Pittsburgh)Meryl A. Butters✉(University of Pittsburgh)Steven M. Albert(University of Pittsburgh)Mary Amanda Dew(University of Pittsburgh)Charles F. Reynolds(University of Pittsburgh)
Abstract
Late-life depression is associated with an increased risk for all-cause dementia, vascular dementia and Alzheimer's disease. The present results suggest that it will be valuable to design clinical trials to investigate the effect of late-life depression prevention on risk of dementia, in particular vascular dementia and Alzheimer's disease.
Dementia and Cognitive Impairment ResearchHealth disparities and outcomesIntergenerational Family Dynamics and CaregivingDementiaVascular dementiaLate life depressionDepression (economics)MedicineMeta-analysisCohort studyDiseaseAlzheimer's diseaseInternal medicine
MeSH terms
AdolescentAdultAgedAged, 80 and overAlzheimer DiseaseChildDepressive DisorderFemaleHumansMaleMiddle AgedRisk FactorsDementia, VascularYoung Adult
Funding
- John A. Hartford Foundation
- Hartford Foundation for Public Giving
- American Foundation for Suicide Prevention
- National Institute on Aging
- National Heart, Lung, and Blood Institute
- National Institute of Mental Health
- National Institute on Minority Health and Health Disparities
Citations
1,263
FWCI
43.28
field-weighted impact
References
40
Percentile
100%
vs. same field & year
Citations per year
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References
The projected effect of risk factor reduction on Alzheimer's disease prevalence
The Lancet Neurology · 2011 · 2,640 citations
Depression and Risk for Alzheimer Disease
Archives of General Psychiatry · 2006 · 1,445 citations
Risk Factors for Alzheimer's Disease: A Prospective Analysis from the Canadian Study of Health and Aging
American Journal of Epidemiology · 2002 · 1,260 citations
The Newcastle-Ottawa Scale (NOS) for Assessing the Quality of Nonrandomised Studies in Meta-Analyses
Medical Entomology and Zoology · 2014 · 17,868 citations
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