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Frequency and Spectrum of Cancers in the Peutz-Jeghers Syndrome
Clinical Cancer Research · 2006 · Vol. 12(10) · pp. 3209–3215
Nicholas Hearle✉(Institute of Cancer Research)Valerié Schumacher(Heinrich Heine University Düsseldorf)Fred H. Menko(Vrije Universiteit Amsterdam)Sylviane Olschwang(Institut Paoli-Calmettes)Lisa A. Boardman(Mayo Clinic)Gilles Thomas(Vrije Universiteit Amsterdam)Josbert J. Keller(Academic Medical Center)Anne Marie Westerman(Erasmus MC)Rodney J. Scott(Hunter Medical Research Institute)Wendy Lim(Institute of Cancer Research)Jill D. Trimbath(Johns Hopkins University)Francis M. Giardiello(Johns Hopkins University)Stephen B. Gruber(University of Michigan–Ann Arbor)G. Johan A. Offerhaus(Academic Medical Center)Felix W.M. de Rooij(Erasmus MC)J. H. P. Wilson(Erasmus MC)Anika Hansmann(Heinrich Heine University Düsseldorf)Gabriela Möslein(Helios Universitätsklinikum Wuppertal)Brigitte Royer‐Pokora(Heinrich Heine University Düsseldorf)Tilman Vogel(Kliniken Maria Hilf)Robin Phillips(St Mark's Hospital)Allan D. Spigelman(UNSW Sydney)Richard S. Houlston(Institute of Cancer Research)
Abstract
The results from our study provide quantitative information on the spectrum of cancers and risks of specific cancer types associated with Peutz-Jeghers syndrome.
Genetic factors in colorectal cancerCholangiocarcinoma and Gallbladder Cancer StudiesMultiple and Secondary Primary CancersSTK11Peutz–Jeghers syndromeMedicineCancerInternal medicineIncidence (geometry)GastroenterologyColorectal cancerBreast cancerOncology
MeSH terms
AMP-Activated Protein Kinase KinasesAdultAgedBreast NeoplasmsFemaleGastrointestinal NeoplasmsHumansMaleMiddle AgedPeutz-Jeghers SyndromeRisk FactorsIncidenceProtein Serine-Threonine KinasesAge of OnsetGerm-Line Mutation
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References
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