article Open AccessTop 10% cited
Mechanisms of progression in native coronary artery disease: role of healed plaque disruption
Heart · 1999 · Vol. 82(3) · pp. 265–268
Jessica M. Mann(St George's, University of London)Melanie J. Davies✉(St George's, University of London)
Abstract
Subclinical episodes of plaque disruption followed by healing are a stimulus to plaque growth that occurs suddenly and is a major factor in causing chronic high grade coronary stenosis. This mechanism would explain the phasic rather than linear progression of coronary disease observed in angiograms carried out annually in patients with chronic ischaemic heart disease.
Coronary Interventions and DiagnosticsCardiac Valve Diseases and TreatmentsAcute Myocardial Infarction ResearchMedicineLumen (anatomy)StenosisSirius RedCoronary arteriesLesionArteryCardiologyStainingInternal medicine
MeSH terms
AgedCollagenCoronary Artery DiseaseHumansImage Processing, Computer-AssistedMaleMiddle AgedWound HealingDeath, Sudden, CardiacDisease Progression
Citations
428
FWCI
8.91
field-weighted impact
References
32
Percentile
98%
vs. same field & year
Citations per year
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References
Coronary Plaque Disruption
Circulation · 1995 · 3,514 citations
Plaque fissuring--the cause of acute myocardial infarction, sudden ischaemic death, and crescendo angina.
Heart · 1985 · 1,993 citations
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