article Open AccessTop 10% cited
A Phase I and Pharmacological Study with Imidazolium-<b> <i>trans-</i> </b>DMSO-imidazole-tetrachlororuthenate, a Novel Ruthenium Anticancer Agent
Clinical Cancer Research · 2004 · Vol. 10(11) · pp. 3717–3727
Jeany M. Rademaker-Lakhai✉(Slotervaartziekenhuis)H.J.G.D. van den Bongard(The Netherlands Cancer Institute)Dick Pluim(Oncode Institute)Jos H. Beijnen(Slotervaartziekenhuis)Jan H.M. Schellens(Oncode Institute)
Abstract
NAMI-A can be administered safely as a 3-h i.v. infusion at a dose of 300 mg/m(2)/day for 5 days, every 3 weeks.
Radiopharmaceutical Chemistry and ApplicationsMetal complexes synthesis and propertiesLung Cancer Treatments and MutationsPharmacokineticsRutheniumPharmacologyToxicityMedicineLimitingAdverse effectChemistryInternal medicineBiochemistry
MeSH terms
AdultAgedAntineoplastic AgentsDimethyl SulfoxideDose-Response Relationship, DrugFemaleHumansMaleMiddle AgedModels, ChemicalOrganometallic CompoundsRutheniumTime FactorsTreatment OutcomeRuthenium Compounds
Citations
820
FWCI
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References
33
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99%
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References
A simple salting out procedure for extracting DNA from human nucleated cells
Nucleic Acids Research · 1988 · 20,510 citations
New Guidelines to Evaluate the Response to Treatment in Solid Tumors
JNCI Journal of the National Cancer Institute · 2000 · 15,689 citations
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