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Perineural Invasion in Squamous Cell Carcinoma of the Head and Neck

Archives of Otolaryngology - Head and Neck Surgery · 1998 · Vol. 124(6) · pp. 637–637

Johannes J. Fagan✉(University of Pittsburgh)Bobby CollinsLeon BarnesFrank D’AmicoEugene N. MyersJonas T. Johnson

Abstract

Perineural invasion of small nerves is associated with an increased risk of local recurrence and cervical metastasis and is, independent of extracapsular spread, a predictor of survival for patients with SCC of the upper aerodigestive tract.

Head and Neck Cancer Studies Ear and Head Tumors Salivary Gland Tumors Diagnosis and TreatmentPerineural invasionMedicineLymphovascular invasionLarynxPerineuriumVascular invasionOtorhinolaryngologyLymphatic systemMetastasisPathology

MeSH terms

Carcinoma, Squamous CellFemaleFollow-Up StudiesHead and Neck NeoplasmsHumansLaryngeal NeoplasmsLymphatic MetastasisMaleMiddle AgedMouth NeoplasmsNeoplasm InvasivenessNeoplasm Recurrence, LocalOropharynxPeripheral NervesPharyngeal Neoplasms

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411

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