articleTop 1% cited

Elevation of Systemic Markers Related to Cardiovascular Diseases in the Peripheral Blood of Periodontitis Patients

Journal of Periodontology · 2000 · Vol. 71(10) · pp. 1528–1534

Bruno G. Loos✉(Academic Center for Dentistry Amsterdam)Jeroen Craandijk(Academic Center for Dentistry Amsterdam)Frans J. Hoek(Academic Medical Center)P. M. E. Wertheim‐van DillenU. van der Velden(Academic Center for Dentistry Amsterdam)

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Abstract

Periodontitis results in higher systemic levels of CRP, IL-6, and neutrophils. These elevated inflammatory factors may increase inflammatory activity in atherosclerotic lesions, potentially increasing the risk for cardiac or cerebrovascular events.

Oral microbiology and periodontitis research Streptococcal Infections and Treatments Oral Health Pathology and TreatmentPeriodontitisMedicineSystemic inflammationInternal medicineInflammationC-reactive proteinGastroenterologyBody mass indexChronic periodontitisImmunology

MeSH terms

AdultAntibodies, BacterialAntibodies, ViralC-Reactive ProteinCardiovascular DiseasesCholesterolCytomegalovirusFemaleHumansImmunoglobulin GLeukocyte CountMaleMiddle AgedPeriodontitisTriglycerides

Citations

804

FWCI

13.43

field-weighted impact

References

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99%

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Citations per year

Cited by

Neuroinflammation: The link between periodontal disease and Alzheimer’s disease