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Primary Perineal Wound Closure After Preoperative Radiotherapy and Abdominoperineal Resection has a High Incidence of Wound Failure

Diseases of the Colon & Rectum · 2005 · Vol. 48(3) · pp. 438–443

Kelli M. Bullard✉(University of Minnesota)Judith L. Trudel(University of Minnesota)Nancy N. Baxter(University of Minnesota)David A. Rothenberger(University of Minnesota)

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Abstract

Wound complications are frequent after abdominoperineal resection and primary closure of the perineum. Preoperative radiation therapy doubles the rate of total and major perineal wound complications. Alternatives to primary perineal closure should be considered, particularly after radiation therapy.

Colorectal Cancer Surgical Treatments Colorectal and Anal Carcinomas Anorectal Disease Treatments and OutcomesMedicineAbdominoperineal resectionSurgeryRadiation therapyComplicationPerineumColorectal surgeryColorectal cancerCancerAbdominal surgery

MeSH terms

AgedCarcinomaCombined Modality TherapyFemaleHumansMaleMiddle AgedPerineumRadiation InjuriesRectal NeoplasmsRetrospective StudiesRisk FactorsSurgical Wound InfectionWound HealingChemotherapy, Adjuvant