review Open AccessTop 1% cited
Mechanisms of Human Papillomavirus-Induced Oncogenesis
Journal of Virology · 2004 · Vol. 78(21) · pp. 11451–11460
Karl Münger✉(Harvard University)Amy Baldwin(Harvard University)Kirsten M. Edwards(Harvard University)Hiroyuki Hayakawa(Harvard University)Christine Nguyen(Harvard University)Michael C. Owens(Harvard University)Miranda Grace(Harvard University)Kyung-Won Huh(Harvard University)
Abstract
Papillomaviruses are small nonenveloped viruses with 55-nm-diameter icosahedral capsids that contain double-stranded DNA genomes of approximately 8,000 bp. They are widely distributed throughout the animal kingdom, specifically infect squamous epithelia, and cause the generation of warts. An
Cervical Cancer and HPV ResearchCancer-related Molecular PathwaysMolecular Biology Techniques and ApplicationsBiologyCarcinogenesisPapillomaviridaeHuman papillomavirusVirologyGeneticsCancer researchCancerCervical cancer
MeSH terms
Cell Transformation, ViralUterine Cervical NeoplasmsDNA-Binding ProteinsFemaleHumansOncogene Proteins, ViralRepressor ProteinsGenome, ViralTelomerasePapillomaviridaeGenomic InstabilityPapillomavirus E7 Proteins
Funding
- National Institutes of Health
Citations
1,032
FWCI
25.72
field-weighted impact
References
156
Percentile
100%
vs. same field & year
Citations per year
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The E6 and E7 genes of the human papillomavirus type 16 together are necessary and sufficient for transformation of primary human keratinocytes
Journal of Virology · 1989 · 1,345 citations
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Cell · 2000 · 28,385 citations
Papillomaviruses and cancer: from basic studies to clinical application
Nature reviews. Cancer · 2002 · 3,997 citations
Evidence for a Causal Association Between Human Papillomavirus and a Subset of Head and Neck Cancers
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