articleTop 10% cited

Synthetic chalcones, flavanones, and flavones as antitumoral agents: Biological evaluation and structure–activity relationships

Bioorganic & Medicinal Chemistry · 2007 · Vol. 15(10) · pp. 3356–3367

Mauricio Cabrera(Universidad de la República)Macarena Simoens(Universidad de la República)Gabriela Falchi(Universidad de la República)María Laura Lavaggi(Universidad de la República)Oscar E. Piro(Consejo Nacional de Investigaciones Científicas y Técnicas)E.E. Castellano(Universidade de São Paulo)Anabel Vidal(Universidad de la República)Amaya Azqueta(Universidad de Navarra)Antonio Monge(Universidad de Navarra)Adela López de Ceráin(Universidad de Navarra)Gabriel Sagrera(Universidad de la República)Gustavo Seoane(Universidad de la República)Hugo Cerecetto✉(Universidad de la República)Mercedes González✉(Universidad de la República)

View via DOI Publisher page

Synthesis and biological activity Synthesis of Organic Compounds Genomics, phytochemicals, and oxidative stressFlavonesChemistryChalconeBiological activityCell cultureComet assayBiochemistryIn vitroMolecular biologyStereochemistry

MeSH terms

Antineoplastic AgentsChromatography, Thin LayerChromosome AberrationsDNA DamageDNA, NeoplasmDrug Screening Assays, AntitumorHumansIndicators and ReagentsMagnetic Resonance SpectroscopySpectrophotometry, InfraredMass SpectrometryStructure-Activity RelationshipX-Ray DiffractionComet AssayCell Line, Tumor

Citations

297

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8.47

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98%

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Cited by

Natural and synthetic 2′-hydroxy-chalcones and aurones: Synthesis, characterization and evaluation of the antioxidant and soybean lipoxygenase inhibitory activity