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Premature Age-Related Comorbidities Among HIV-Infected Persons Compared With the General Population

Clinical Infectious Diseases · 2011 · Vol. 53(11) · pp. 1120–1126

Giovanni Guaraldi✉Gabriella Orlando(University of Modena and Reggio Emilia)Stefano Zona(University of Modena and Reggio Emilia)Marianna Menozzi(University of Modena and Reggio Emilia)Federica Carli(University of Modena and Reggio Emilia)Elisa Garlassi(University of Modena and Reggio Emilia)A BertiElisa RossiAlberto Roverato(University of Bologna)FJ Palella(Northwestern University)

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Abstract

Specific age-related NICMs and Pp were more common among HIV-infected patients than in the general population. The prevalence of Pp in HIV-infected persons anticipated Pp prevalence observed in the general population among persons who were 10 years older, and HIV-specific cofactors (lower nadir CD4 cell count and more prolonged ART exposure) were identified as risk factors. These data support the need for earlier screening for NICMs in HIV-infected patients.

HIV-related health complications and treatments HIV/AIDS Research and Interventions Pneumocystis jirovecii pneumonia detection and treatmentMedicineDiabetes mellitusCohortInternal medicineOdds ratioPopulationLogistic regressionCohort studyEndocrinology

MeSH terms

AdultAge FactorsCardiovascular DiseasesDiabetes MellitusFemaleHumansHypertensionItalyMaleMiddle AgedRisk FactorsHIV InfectionsComorbidityPrevalenceCase-Control Studies

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