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Use of oral glucocorticoids and risk of cardiovascular and cerebrovascular disease in a population based case–control study

Heart · 2004 · Vol. 90(8) · pp. 859–865
Patrick C. SouvereinAnick BérardTjeerd van StaaCyrus CooperToine C. G. EgbertsH.G.M. LeufkensBR Walker

Abstract

Oral glucocorticoid use was identified as a risk factor for heart failure. However, the evidence remains observational and only a randomised controlled trial of glucocorticoid treatment versus other disease modifying agents is likely to distinguish the importance of the underlying disease activity from its treatment in predicting cardiovascular outcomes.

Thyroid Disorders and TreatmentsAdrenal Hormones and DisordersAsthma and respiratory diseasesMedicineOdds ratioInternal medicineConfidence intervalPopulationRheumatoid arthritisCohortStroke (engine)Heart failureMedical prescription

MeSH terms

Administration, OralAgedAged, 80 and overCardiovascular DiseasesCerebrovascular DisordersDose-Response Relationship, DrugGlucocorticoidsHumansMiddle AgedRisk FactorsCohort StudiesCase-Control Studies
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References
Modeling and variable selection in epidemiologic analysis.
American Journal of Public Health · 1989 · 2,216 citations
Use of Inhaled Corticosteroids and Risk of Fractures
Journal of Bone and Mineral Research · 2001 · 1,314 citations
Atherosclerosis — An Inflammatory Disease
New England Journal of Medicine · 1999 · 21,632 citations
Use of Oral Corticosteroids and Risk of Fractures
Journal of Bone and Mineral Research · 2000 · 1,242 citations
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