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Hypothesis: Microtubule Instability and Paired Helical Filament Formation in the Alzheimer Disease Brain Are Related to Apolipoprotein E Genotype
Experimental Neurology · 1994 · Vol. 125(2) · pp. 163–171
Warren J. Strittmatter✉(Duke University)Karl H. Weisgraber(Durham VA Medical Center)Michel Goedert(Duke Medical Center)Ann M. Saunders(Duke University)David Huang(University of California, San Francisco)Elizabeth H. Corder(Durham VA Medical Center)Liming Dong(Durham VA Medical Center)Ross Jakes(Duke University)Mark J. Alberts(Duke University)John R. Gilbert(Medical Research Council)Seol‐Heui Han(Medical Research Council)Christine Hulette(Durham VA Medical Center)Gillian Einstein(University of California, San Francisco)Donald E. Schmechel(Medical Research Council)Margaret A. Pericak‐Vance(Durham VA Medical Center)Allen D. Roses(Gladstone Institutes)
Alzheimer's disease research and treatmentsMicrotubule and mitosis dynamicsMitochondrial Function and PathologyApolipoprotein EMicrotubuleTau proteinAlzheimer's diseaseAlleleNeuroscienceBiologyDiseaseGeneticsGene
MeSH terms
Alzheimer DiseaseApolipoproteins EChromosomesHumansGenetic LinkageMicrotubulesPhosphorylationAmyloid beta-PeptidesNeurofibrillary Tanglestau ProteinsApolipoprotein E4
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