Scinovex
article Open AccessTop 1% cited

Tomotherapy: A new concept for the delivery of dynamic conformal radiotherapy

Medical Physics · 1993 · Vol. 20(6) · pp. 1709–1719
T MackieTimothy HolmesStuart SwerdloffPaul ReckwerdtJoseph O. DeasyJames N. YangBhudatt R. PaliwalTimothy Kinsella

Abstract

Tomotherapy, literally "slice therapy," is a proposal for the delivery of radiation therapy with intensity-modulated strips of radiation. The proposed method employs a linear accelerator, or another radiation-emitting device, which would be mounted on a ring gantry like a CT scanner. The patient would move through the bore of the gantry simultaneously with gantry rotation. The intensity modulation would be performed by temporally modulated multiple independent leaves that open and close across the slit opening. At any given time, any leaf would be (1) closed, covering a portion of the slit, (2) open, allowing radiation through, or (3) changing between these states. This method would result in the delivery of highly conformal radiation. Overall treatment times should be comparable with contemporary treatment delivery times. The ring gantry would make it convenient to mount a narrow multisegmented megavoltage detector system for beam verification and a CT scanner on the treatment unit. Such a treatment unit could become a powerful tool for treatment planning, conformal treatment, and verification using tomographic images. The physical properties of this treatment delivery are evaluated and the fundamental design specifications are justified.

Advanced Radiotherapy TechniquesMedical Imaging Techniques and ApplicationsWireless Body Area NetworksTomotherapyScannerRadiation therapyConformal mapRadiation treatment planningComputer scienceIntensity modulationDosimetryLinear particle acceleratorRotation (mathematics)

MeSH terms

HumansMathematicsModels, TheoreticalRadiotherapyTomography, X-Ray Computed
Citations
1,063
FWCI
16.97
field-weighted impact
References
0
Percentile
100%
vs. same field & year
Citations per year
Cited by
Intensity-modulated radiotherapy: current status and issues of interest
International Journal of Radiation Oncology*Biology*Physics · 2001 · 760 citations
Intensity modulation methods for proton radiotherapy
Physics in Medicine and Biology · 1999 · 533 citations
Volumetric modulated arc therapy: IMRT in a single gantry arc
Medical Physics · 2007 · 1,830 citations
IMRT: a review and preview
Physics in Medicine and Biology · 2006 · 490 citations
Dose calculations for external photon beams in radiotherapy
Physics in Medicine and Biology · 1999 · 493 citations
Citation Network

How this paper connects to the literature. Drag to explore, click any node to open that paper.