article Open AccessTop 1% cited
aph-1 and pen-2 Are Required for Notch Pathway Signaling, γ-Secretase Cleavage of βAPP, and Presenilin Protein Accumulation
Developmental Cell · 2002 · Vol. 3(1) · pp. 85–97
Ross S. Francis(Exelixis (United States))Garth McGrath(Exelixis (United States))Jianhua Zhang(Exelixis (United States))David A. Ruddy(Exelixis (United States))Mary Sym(Exelixis (United States))Javier Apfeld(Exelixis (United States))Monique Nicoll(Exelixis (United States))Mark Maxwell(Exelixis (United States))Bing Hai(Exelixis (United States))Michael C. Ellis(Exelixis (United States))Annette L. Parks(Exelixis (United States))Wei Xu(Exelixis (United States))Jinhe LiMark E. GurneyRichard L. MyersCarol S. HimesRonald R. HiebschCara RubleJeffrey S. NyeDaniel Curtis✉(Exelixis (United States))
Alzheimer's disease research and treatmentsRetinal Development and DisordersNuclear Receptors and SignalingPresenilinBiologyNotch signaling pathwayCell biologyAmyloid precursor protein secretaseCleavage (geology)Signal transductionAmyloid precursor proteinInternal medicineAlzheimer's disease
MeSH terms
Alzheimer DiseaseAnimalsCell MembraneCells, CulturedCloning, MolecularDrosophila melanogasterEnhancer Elements, GeneticGlucagonHumansIntracellular MembranesMembrane ProteinsMolecular Sequence DataMutationPeptide FragmentsEndopeptidases
Funding
- Exelixis
Citations
795
FWCI
38.89
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48
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100%
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