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Rapid Healing of Venous Ulcers and Lack of Clinical Rejection With an Allogeneic Cultured Human Skin Equivalent

Archives of Dermatology · 1998 · Vol. 134(3) · pp. 293–293

Vincent Falanga✉(University of Miami)

Abstract

Treatment with HSE healed venous ulcers more rapidly and in more patients than compression therapy alone. There was no clinical or laboratory evidence of rejection or sensitization in response to HSE application. These data suggest that HSE represents a significant advance in the treatment of venous ulcers, particularly those that are difficult to heal.

Wound Healing and Treatments Diagnosis and Treatment of Venous Diseases Pressure Ulcer Prevention and ManagementMedicineAdverse effectSurgeryRandomized controlled trialWound healingClinical trialInternal medicine

MeSH terms

AgedAnimalsAntibodiesBandagesCattleCollagenCytotoxicity, ImmunologicFemaleFibroblastsGraft RejectionHLA AntigensHumansMaleProspective StudiesRecurrence

Citations

664

FWCI

56.70

field-weighted impact

References

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100%

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Cited by

Management of venous leg ulcers: Clinical practice guidelines of the Society for Vascular Surgery® and the American Venous Forum