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Global distribution and prevalence of hepatitis C virus genotypes

Hepatology · 2014 · Vol. 61(1) · pp. 77–87

Jane P. Messina✉(University of Oxford)Isla Humphreys(University of Oxford)Abraham D. Flaxman(Institute for Health Metrics and Evaluation)Anthony Brown(University of Oxford)Graham Cooke(Imperial College London)Oliver G. Pybus(University of Oxford)Eleanor Barnes✉(Medawar Building for Pathogen Research)

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Abstract

Although genotype 1 is most common worldwide, nongenotype 1 HCV cases—which are less well served by advances in vaccine and drug development—still comprise over half of all HCV cases. Relative genotype proportions are needed to inform healthcare models, which must be geographically tailored to specific countries or regions in order to improve access to new treatments. Genotype surveillance data are needed from many countries to improve estimates of unmet need.

Hepatitis C virus research Liver Disease Diagnosis and Treatment Hepatitis B Virus StudiesGenotypeHepatitis C virusPopulationGlobal healthVirologyDemographyMedicineBiologyEnvironmental healthPublic health