article Open AccessTop 1% cited
Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis
Cancer Cell · 2006 · Vol. 10(1) · pp. 51–64
Kurt Degenhardt(Rutgers, The State University of New Jersey)Robin MathewBrian Beaudoin(Rutgers, The State University of New Jersey)Kevin Bray(Rutgers, The State University of New Jersey)Diana Anderson(Rutgers, The State University of New Jersey)Guanghua Chen(Rutgers, The State University of New Jersey)Chandreyee Mukherjee(Howard Hughes Medical Institute)Yufang ShiCéline GélinasYongjun FanDeirdre A. Nelson(Howard Hughes Medical Institute)Xin JinEileen White✉(Rutgers, The State University of New Jersey)
Autophagy in Disease and TherapyEndoplasmic Reticulum Stress and DiseaseHeme Oxygenase-1 and Carbon MonoxideAutophagyApoptosisProgrammed cell deathBiologyNecrosisCarcinogenesisCell biologyInflammationCancer researchTumor necrosis factor alpha
MeSH terms
Beclin-1AnimalsAutophagyCell Line, TransformedCell SurvivalCell Transformation, NeoplasticHeLa CellsHumansInflammationMacrophagesMice, NudeModels, BiologicalNecrosisNeoplasmsProteins
Funding
- Howard Hughes Medical Institute
- National Institutes of Health
Citations
1,975
FWCI
43.47
field-weighted impact
References
60
Percentile
100%
vs. same field & year
Citations per year
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References
Cell Death
Cell · 2004 · 4,620 citations
Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes
Nature Cell Biology · 2004 · 1,330 citations
Necrosis: a specific form of programmed cell death?
Experimental Cell Research · 2003 · 709 citations
The Hallmarks of Cancer
Cell · 2000 · 28,385 citations
Smoldering and polarized inflammation in the initiation and promotion of malignant disease
Cancer Cell · 2005 · 1,757 citations
Development by Self-Digestion
Developmental Cell · 2004 · 3,629 citations
The Bcl-2 family: roles in cell survival and oncogenesis
Oncogene · 2003 · 1,448 citations
In Vivo Analysis of Autophagy in Response to Nutrient Starvation Using Transgenic Mice Expressing a Fluorescent Autophagosome Marker
Molecular Biology of the Cell · 2003 · 2,285 citations
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