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Relative apical sparing of longitudinal strain using two-dimensional speckle-tracking echocardiography is both sensitive and specific for the diagnosis of cardiac amyloidosis
Heart · 2012 · Vol. 98(19) · pp. 1442–1448
Dermot Phelan(Cleveland Clinic)Patrick Collier(Cleveland Clinic)Paaladinesh Thavendiranathan(Cleveland Clinic)Zoran Popović(Cleveland Clinic)Mazen Hanna(Cleveland Clinic)Juan Carlos Plana(Cleveland Clinic)Thomas H. Marwick(Cleveland Clinic)James D. Thomas✉(Cleveland Clinic)
Abstract
CA is characterised by regional variations in LS from base to apex. A relative 'apical sparing' pattern of LS is an easily recognisable, accurate and reproducible method of differentiating CA from other causes of LV hypertrophy.
Amyloidosis: Diagnosis, Treatment, OutcomesCardiovascular Function and Risk FactorsParathyroid Disorders and TreatmentsMedicineCardiac amyloidosisCardiologyInternal medicineApex (geometry)Hypertrophic cardiomyopathyBasal (medicine)Muscle hypertrophyAmyloidosisStenosis
MeSH terms
AdultAgedAged, 80 and overAmyloidosisBiomechanical PhenomenaBiopsyDiagnosis, DifferentialElectrocardiographyFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedCardiomyopathiesOhio
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References
How does the extracellular matrix direct gene expression?
Journal of Theoretical Biology · 1982 · 1,513 citations
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