articleTop 10% cited
Deregulation of sphingolipid metabolism in Alzheimer's disease
Neurobiology of Aging · 2008 · Vol. 31(3) · pp. 398–408
Xingxuan He(Icahn School of Medicine at Mount Sinai)Yu HuangBin LiCheng‐Xin GongEdward H. Schuchman✉(Icahn School of Medicine at Mount Sinai)
Sphingolipid Metabolism and SignalingAlzheimer's disease research and treatmentsLysosomal Storage Disorders ResearchCeramideSphingolipidSphingomyelinSphingosineTauopathyBiologyCell biologyLipid signalingApoptosisSphingosine-1-phosphate
MeSH terms
AgedAlzheimer DiseaseAnimalsBrainCells, CulturedCeramidesHumansLysophospholipidsNeuronsPhosphorylationSphingolipidsSphingomyelin PhosphodiesteraseSphingomyelinsSphingosineAmyloid beta-Peptides
Funding
- National Institutes of Health
Citations
517
FWCI
7.45
field-weighted impact
References
60
Percentile
98%
vs. same field & year
Citations per year
References
Substantial sulfatide deficiency and ceramide elevation in very early Alzheimer's disease: potential role in disease pathogenesis
Journal of Neurochemistry · 2002 · 626 citations
Evidence for Apoptotic Cell Death in Alzheimer's Disease
Experimental Neurology · 1995 · 484 citations
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