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Predicting the extent of heterogeneity in meta-analysis, using empirical data from the Cochrane Database of Systematic Reviews

International Journal of Epidemiology · 2012 · Vol. 41(3) · pp. 818–827
Rebecca TurnerJonathan DaveyMike ClarkeSimon G. ThompsonJulian P. T. Higgins

Abstract

Meta-analysis characteristics were strongly associated with the degree of between-study heterogeneity, and predictive distributions for heterogeneity differed substantially across settings. The informative priors provided will be very beneficial in future meta-analyses including few studies.

Meta-analysis and systematic reviewsStatistical Methods in Clinical TrialsReliability and Agreement in MeasurementMeta-analysisStudy heterogeneityRandom effects modelSystematic reviewMedicinePsychological interventionOdds ratioPooled varianceMeta-regressionStatistics

MeSH terms

Bayes TheoremHumansResearch DesignMeta-Analysis as TopicOutcome Assessment, Health Care

Funding

  • Medical Research Council
Citations
829
FWCI
27.09
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