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Transplantation of hypoxia-preconditioned mesenchymal stem cells improves infarcted heart function via enhanced survival of implanted cells and angiogenesis

Journal of Thoracic and Cardiovascular Surgery · 2008 · Vol. 135(4) · pp. 799–808
Xinyang HuShan Ping YuJamie L. FraserZhongyang LuMolly E. OgleJianan WangLing Wei
Mesenchymal stem cell researchTissue Engineering and Regenerative MedicineElectrospun Nanofibers in Biomedical ApplicationsAngiogenesisMesenchymal stem cellHypoxia (environmental)TransplantationStem cellCardiologyMedicineBiomedical engineeringCancer researchInternal medicine

MeSH terms

AnimalsHypoxiaGraft SurvivalMice, TransgenicMyocardial InfarctionCell DeathMyocardial IschemiaApoptosisNeovascularization, PhysiologicIschemic PreconditioningParacrine CommunicationMesenchymal Stem Cell TransplantationMiceMesenchymal Stem Cells

Funding

  • American Heart Association
  • National Institutes of Health
  • National Center for Research Resources
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Transplantation of hypoxia-preconditioned mesenchymal stem cells improves infarcted heart function via enhanced survival of implanted cells and angiogenesis · Scinovex