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Obstructive Sleep Apnea–Hypopnea and Incident Stroke: The Sleep Heart Health Study

American Journal of Respiratory and Critical Care Medicine · 2010 · Vol. 182(2) · pp. 269–277
Susan RedlineGayane YenokyanDaniel J. GottliebEyal ShaharGeorge O'connorHelaine E. ResnickMarie Diener‐WestMark SandersPhilip A. WolfEstella M. GeraghtyTauqeer AliMichael LebowitzNaresh M. Punjabi

Abstract

The strong adjusted association between ischemic stroke and OAHI in community-dwelling men with mild to moderate sleep apnea suggests that this is an appropriate target for future stroke prevention trials.

Obstructive Sleep Apnea ResearchCardiovascular and Diving-Related ComplicationsNeuroscience of respiration and sleepMedicineObstructive sleep apneaHazard ratioStroke (engine)Sleep apneaPolysomnographyQuartileConfidence intervalInternal medicineHypopnea

MeSH terms

AgedFemaleHumansLongitudinal StudiesMaleMiddle AgedProspective StudiesSeverity of Illness IndexSex FactorsProportional Hazards ModelsPolysomnographySleep Apnea, ObstructiveStroke

Funding

  • University of Minnesota
  • University of Washington
  • Johns Hopkins University
  • Case Western Reserve University
  • Strong
  • York University
  • University of California, Davis
Citations
1,249
FWCI
44.26
field-weighted impact
References
45
Percentile
100%
vs. same field & year
Citations per year
References
Prevalence of Sleep-disordered Breathing in Women
American Journal of Respiratory and Critical Care Medicine · 2001 · 1,579 citations
Association of Nocturnal Arrhythmias with Sleep-disordered Breathing
American Journal of Respiratory and Critical Care Medicine · 2006 · 1,240 citations
Heart Disease and Stroke Statistics—2008 Update
Circulation · 2007 · 3,728 citations
Sleep-disordered Breathing and Cardiovascular Disease
American Journal of Respiratory and Critical Care Medicine · 2001 · 2,900 citations
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