article Open AccessTop 1% cited
Knockout of Glutamate Transporters Reveals a Major Role for Astroglial Transport in Excitotoxicity and Clearance of Glutamate
Neuron · 1996 · Vol. 16(3) · pp. 675–686
Jeffrey D. Rothstein✉(Johns Hopkins University)Margaret Dykes‐Hoberg(Johns Hopkins University)Carlos A. Pardo(Johns Hopkins University)Lynn A. Bristol(Johns Hopkins University)Jin Li(Johns Hopkins University)Ralph W. Kuncl(Johns Hopkins University)Yoshikatsu Kanai(Kyorin University)Matthias A. Hediger(Harvard University)Yanfeng WangJerry P SchielkeDevin Welty
Neuroscience and Neuropharmacology ResearchAmino Acid Enzymes and MetabolismMolecular Sensors and Ion DetectionExcitotoxicityGlutamate receptorExcitatory amino-acid transporterNeuroscienceTransporterChemistryKnockout mouseCell biologyBiologyBiochemistry
MeSH terms
AnimalsAstrocytesCells, CulturedGlutamatesHippocampusImmunohistochemistryMaleMicroscopy, ElectronSpinal CordGene ExpressionOligonucleotides, AntisenseRats, Sprague-DawleyATP-Binding Cassette TransportersAmino Acid Transport System X-AGRats
Funding
- Muscular Dystrophy Association
- National Institutes of Health
Citations
2,528
FWCI
31.45
field-weighted impact
References
35
Percentile
100%
vs. same field & year
Citations per year
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References
The release and uptake of excitatory amino acids
Trends in Pharmacological Sciences · 1990 · 1,091 citations
Fine structural localization of glutamine synthetase in astrocytes of rat brain
Brain Research · 1979 · 1,344 citations
Localization of neuronal and glial glutamate transporters
Neuron · 1994 · 1,694 citations
Selective loss of glial glutamate transporter GLT‐1 in amyotrophic lateral sclerosis
Annals of Neurology · 1995 · 1,459 citations
THE EFFECT OF CHANGES IN THE CALCIUM CONTENT OF THE CEREBROSPINAL FLUID ON SPINAL REFLEX ACTIVITY IN THE DOG
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