article Open AccessTop 1% cited
Regulated Translation Initiation Controls Stress-Induced Gene Expression in Mammalian Cells
Molecular Cell · 2000 · Vol. 6(5) · pp. 1099–1108
Heather P. Harding✉Isabel Novoa(New York University)Yuhong Zhang(New York University)Huiqing Zeng(New York University)Ronald C. Wek(Indiana University School of Medicine)Matthieu Schapira(New York University)David Ron(New York University)
Endoplasmic Reticulum Stress and DiseaseRNA regulation and diseaseViral Infectious Diseases and Gene Expression in InsectsBiologyEIF4EBP1Integrated stress responseATF4EIF4A1eIF2Translation (biology)Cell biologyEukaryotic translation initiation factor 4 gammaInitiation factor
MeSH terms
Endoplasmic Reticulum Chaperone BiPAmino AcidsAnimalsCarrier ProteinsCell LineEndoplasmic ReticulumGene Expression RegulationCricetinaeHeat-Shock ProteinsMammalsMutationPeptide Chain Initiation, TranslationalPhosphorylationProtein DenaturationProtein Kinases
Citations
3,216
FWCI
20.31
field-weighted impact
References
46
Percentile
100%
vs. same field & year
Citations per year
Cited by
XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response
Molecular and Cellular Biology · 2003 · 2,053 citations
The Role for Endoplasmic Reticulum Stress in Diabetes Mellitus
Endocrine Reviews · 2007 · 1,158 citations
Coping with stress: eIF2 kinases and translational control
Biochemical Society Transactions · 2006 · 1,285 citations
Pharmacological brake-release of mRNA translation enhances cognitive memory
eLife · 2013 · 729 citations
<b>Stress Granule Assembly Is Mediated by Prion-like Aggregation of TIA-1</b>
Molecular Biology of the Cell · 2004 · 994 citations
Minocycline: far beyond an antibiotic
British Journal of Pharmacology · 2013 · 919 citations
Feedback Inhibition of the Unfolded Protein Response by <i>GADD34</i>-Mediated Dephosphorylation of eIF2α
The Journal of Cell Biology · 2001 · 1,357 citations
Cellular response to endoplasmic reticulum stress: a matter of life or death
Cell Death and Differentiation · 2006 · 682 citations
References
Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response
Nature Cell Biology · 2000 · 2,842 citations
Perk Is Essential for Translational Regulation and Cell Survival during the Unfolded Protein Response
Molecular Cell · 2000 · 1,997 citations
CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum
Genes & Development · 1998 · 2,003 citations
Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls
Genes & Development · 1999 · 2,249 citations
Mammalian Transcription Factor ATF6 Is Synthesized as a Transmembrane Protein and Activated by Proteolysis in Response to Endoplasmic Reticulum Stress
Molecular Biology of the Cell · 1999 · 2,020 citations
Translational control
Journal of Cellular Biochemistry · 1991 · 432 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.