article Open AccessTop 1% cited
Markers of Inflammation, Coagulation, and Renal Function Are Elevated in Adults with HIV Infection
The Journal of Infectious Diseases · 2010 · Vol. 201(12) · pp. 1788–1795
Jacqueline Neuhaus✉(University of Minnesota)David R. Jacobs(University of Minnesota)Jason V. Baker(University of Minnesota System)Alexandra Calmy(University of Geneva)Daniel Duprez(University of Minnesota System)Alberto La Rosa(Asociación Civil Impacta Salud y Educación)Lewis H. Kuller(University of Pittsburgh)Sarah Pett(UNSW Sydney)Matti Ristola(University of Helsinki)Michael J. Ross(Icahn School of Medicine at Mount Sinai)Michael G. Shlipak(University of California, San Francisco)Russell P. Tracy(University of Vermont)James D. Neaton(University of Minnesota System)
Abstract
hsCRP, IL-6, D-dimer, and cystatin C levels are elevated in persons with HIV infection and remain so even after HIV RNA levels are suppressed with antiretroviral therapy. Additional research is needed on the pathophysiology of HIV-induced activation of inflammatory and coagulation pathways, to guide potential interventions.
HIV-related health complications and treatmentsHIV/AIDS Research and InterventionsPneumocystis jirovecii pneumonia detection and treatmentHuman immunodeficiency virus (HIV)ImmunologyInflammationCoagulationRenal functionMedicineInternal medicine
MeSH terms
AdultAgedBlood Coagulation DisordersC-Reactive ProteinFemaleFibrin Fibrinogen Degradation ProductsHumansInflammationKidney DiseasesMaleMiddle AgedBiomarkersHIV InfectionsInterleukin-6Anti-HIV Agents
Funding
- National Institutes of Health
- National Heart, Lung, and Blood Institute
- National Institute of Allergy and Infectious Diseases
Citations
856
FWCI
50.26
field-weighted impact
References
37
Percentile
100%
vs. same field & year
Citations per year
References
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PLoS Medicine · 2008 · 1,595 citations
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American Journal of Epidemiology · 2002 · 3,896 citations
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Clinical Chemistry · 1997 · 799 citations
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