articleTop 10% cited
Dynamics of HIV viremia and antibody seroconversion in plasma donors
AIDS · 2003 · Vol. 17(13) · pp. 1871–1879
Eberhard Fiebig(San Francisco General Hospital)David J. Wright(Westat (United States))B. D. Rawal(Memorial Blood Centers)Patricia E. Garrett(Boston Biomedical (United States))Richard Schumacher(Boston Biomedical (United States))Lorraine Peddada(Alpha Medical (Slovakia))Charles M. Heldebrant(Alpha Medical (Slovakia))Richard Smith(National Research Institute)Andrew Conrad(National Research Institute)Steven Kleinman(University of Victoria)Michael P. Busch✉(Memorial Blood Centers)
Abstract
The sequential emergence of assay reactivity allows the classification of primary HIV-1 infection into distinct laboratory stages, which may facilitate the diagnosis of recent infection and stratification of patients enrolled in clinical trials. Quantitative analysis of preseroconversion replication rates of HIV is useful for projecting the yield and predictive value of assays targeting primary HIV infection.
HIV Research and TreatmentHIV/AIDS Research and InterventionsHIV/AIDS drug development and treatmentViremiaSeroconversionViral loadVirologyAntibodyViral diseaseAntigenImmunologyMedicineHuman immunodeficiency virus (HIV)
MeSH terms
Blood DonorsHIV SeropositivityHumansImmunoenzyme TechniquesRetrospective StudiesRNA, ViralViremiaBiomarkersHIV AntibodiesHIV-1HIV InfectionsHIV Core Protein p24Disease ProgressionViral Load
Funding
- U.S. Food and Drug Administration
Citations
1,290
FWCI
4.66
field-weighted impact
References
21
Percentile
97%
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Citations per year
Cited by
HIV-1 Transmission, by Stage of Infection
The Journal of Infectious Diseases · 2008 · 667 citations
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