articleTop 1% cited
Aerobic Exercise Training Increases Brain Volume in Aging Humans
The Journals of Gerontology Series A · 2006 · Vol. 61(11) · pp. 1166–1170
Stanley J. Colcombe✉Kirk I. Erickson(University of Illinois Urbana-Champaign)Paige E. Scalf(University of Illinois Urbana-Champaign)Jennifer Kim(University of Illinois Urbana-Champaign)Ruchika Shaurya Prakash(University of Illinois Urbana-Champaign)Edward McAuley(University of Illinois Urbana-Champaign)Steriani Elavsky(University of Illinois Urbana-Champaign)David X. Márquez(University of Illinois Urbana-Champaign)Hu L(University of Illinois Urbana-Champaign)Arthur F. Kramer
Abstract
These results suggest that cardiovascular fitness is associated with the sparing of brain tissue in aging humans. Furthermore, these results suggest a strong biological basis for the role of aerobic fitness in maintaining and enhancing central nervous system health and cognitive functioning in older adults.
Cardiovascular Health and Disease PreventionCardiovascular Disease and AdiposityAdvanced Neuroimaging Techniques and ApplicationsAerobic exerciseBrain Structure and FunctionBrain agingCognitionPhysical fitnessCardiovascular fitnessPhysical medicine and rehabilitationFunctional trainingVO2 maxMagnetic resonance imaging
MeSH terms
AdolescentAdultAgedAgingBrainFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedOrgan SizeOxygen ConsumptionExerciseImaging, Three-Dimensional
Funding
- National Institute on Aging
Citations
2,102
FWCI
24.34
field-weighted impact
References
25
Percentile
100%
vs. same field & year
Citations per year
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References
Accurate, Robust, and Automated Longitudinal and Cross-Sectional Brain Change Analysis
NeuroImage · 2002 · 2,038 citations
Exercise, experience and the aging brain1
Neurobiology of Aging · 2002 · 529 citations
Common regions of the human frontal lobe recruited by diverse cognitive demands
Trends in Neurosciences · 2000 · 2,546 citations
Exercise: a behavioral intervention to enhance brain health and plasticity
Trends in Neurosciences · 2002 · 2,670 citations
Fitness Effects on the Cognitive Function of Older Adults
Psychological Science · 2003 · 3,727 citations
A Voxel-Based Morphometric Study of Ageing in 465 Normal Adult Human Brains
NeuroImage · 2001 · 4,577 citations
Segmentation of brain MR images through a hidden Markov random field model and the expectation-maximization algorithm
IEEE Transactions on Medical Imaging · 2001 · 7,255 citations
Aerobic Fitness Reduces Brain Tissue Loss in Aging Humans
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