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Sleep: A Health Imperative

SLEEP · 2012 · Vol. 35(6) · pp. 727–734
Faith S. LuysterPatrick J. StrolloPhyllis C. ZeeJames K. Walsh

Abstract

Chronic sleep deficiency, defined as a state of inadequate or mistimed sleep, is a growing and underappreciated determinant of health status. Sleep deprivation contributes to a number of molecular, immune, and neural changes that play a role in disease development, independent of primary sleep disorders. These changes in biological processes in response to chronic sleep deficiency may serve as etiological factors for the development and exacerbation of cardiovascular and metabolic diseases and, ultimately, a shortened lifespan. Sleep deprivation also results in significant impairments in cognitive and motor performance which increase the risk of motor vehicle crashes and work-related injuries and fatal accidents. The American Academy of Sleep Medicine and the Sleep Research Society have developed this statement to communicate to national health stakeholders the current knowledge which ties sufficient sleep and circadian alignment in adults to health.

Sleep and related disordersSleep and Work-Related FatigueCircadian rhythm and melatoninSleep (system call)Sleep deprivationMedicineSleep medicineDiseaseSleep debtExacerbationGerontologyCognitionPsychology

MeSH terms

AccidentsAdultCardiovascular DiseasesFemaleHealth StatusHumansMaleNeoplasmsObesitySleepSleep Deprivation

Funding

  • Eli Lilly and Company
  • Pfizer
  • GlaxoSmithKline
  • Sleep Research Society
  • ResMed
Citations
846
FWCI
31.69
field-weighted impact
References
109
Percentile
100%
vs. same field & year
Citations per year
References
Adverse Effects of Modest Sleep Restriction on Sleepiness, Performance, and Inflammatory Cytokines
The Journal of Clinical Endocrinology & Metabolism · 2004 · 1,048 citations
The link between fatigue and safety
Accident Analysis & Prevention · 2010 · 776 citations
Mortality Associated With Sleep Duration and Insomnia
Archives of General Psychiatry · 2002 · 1,616 citations
<i>Sleep Deprivation and Vigilant Attention</i>
Annals of the New York Academy of Sciences · 2008 · 1,175 citations
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