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Integrating a 1.5 T MRI scanner with a 6 MV accelerator: proof of concept

Physics in Medicine and Biology · 2009 · Vol. 54(12) · pp. N229–N237
Bas W. RaaymakersJ J W LagendijkJohan OverwegJ G M KokAlexander RaaijmakersEllen M. KerkhofR W van der PutI MeijsingS.P.M. CrijnsF. BenedossoMarco van VulpenC H W de GraaffJoseph H. AllenKevin J. Brown

Abstract

At the UMC Utrecht, The Netherlands, we have constructed a prototype MRI accelerator. The prototype is a modified 6 MV Elekta (Crawley, UK) accelerator next to a modified 1.5 T Philips Achieva (Best, The Netherlands) MRI system. From the initial design onwards, modifications to both systems were aimed to yield simultaneous and unhampered operation of the MRI and the accelerator. Indeed, the simultaneous operation is shown by performing diagnostic quality 1.5 T MRI with the radiation beam on. No degradation of the performance of either system was found. The integrated 1.5 T MRI system and radiotherapy accelerator allow simultaneous irradiation and MR imaging. The full diagnostic imaging capacities of the MRI can be used; dedicated sequences for MRI-guided radiotherapy treatments will be developed. This proof of concept opens the door towards a clinical prototype to start testing MRI-guided radiation therapy (MRIgRT) in the clinic.

Advanced Radiotherapy TechniquesMedical Imaging Techniques and ApplicationsRadiation Therapy and DosimetryScannerComputer scienceRadiation therapyMedical physicsNuclear medicineProof of conceptLinear particle acceleratorMagnetic resonance imagingMedicineBeam (structure)

MeSH terms

Equipment DesignMagnetic Resonance ImagingParticle AcceleratorsPilot ProjectsRadiotherapy, Computer-AssistedSystems IntegrationEquipment Failure Analysis

Funding

  • Nederlandse Organisatie voor Wetenschappelijk Onderzoek
  • Stichting voor de Technische Wetenschappen
Citations
598
FWCI
24.46
field-weighted impact
References
17
Percentile
100%
vs. same field & year
Citations per year
References
MRI/linac integration
Radiotherapy and Oncology · 2007 · 505 citations
Flat-panel cone-beam computed tomography for image-guided radiation therapy
International Journal of Radiation Oncology*Biology*Physics · 2002 · 1,322 citations
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