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The neural correlates of attention deficit hyperactivity disorder: an ALE meta‐analysis

Journal of Child Psychology and Psychiatry · 2006 · Vol. 47(10) · pp. 1051–1062

Abstract

To date, the most consistent findings in the neuroimaging literature of ADHD are deficits in neural activity within fronto-striatal and fronto-parietal circuits. The distributed nature of these results fails to support models emphasizing dysfunction in any one frontal sub-region. While our findings are suggestive of the primacy of deficits in frontal-based neural circuitry underlying ADHD, we discuss potential biases in the literature that need to be addressed before such a conclusion can be fully embraced.

Attention Deficit Hyperactivity DisorderFunctional Brain Connectivity StudiesNeural and Behavioral Psychology StudiesPsychologyNeuroimagingPrefrontal cortexNeuroscienceDorsolateral prefrontal cortexAnterior cingulate cortexAttention deficit hyperactivity disorderInferior frontal gyrusMiddle frontal gyrusFunctional neuroimaging

MeSH terms

AdolescentAttention Deficit Disorder with HyperactivityBasal GangliaChildCorpus StriatumFrontal LobeGyrus CinguliHumansMagnetic Resonance ImagingNerve NetParietal LobeThalamusPositron-Emission Tomography
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