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Correlation between exhaled nitric oxide, sputum eosinophils, and methacholine responsiveness in patients with mild asthma.
Thorax · 1998 · Vol. 53(2) · pp. 91–95
Anon Jatakanon✉(Imperial College London)Sai Kiang Lim(Imperial College London)Sergei A. Kharitonov(Imperial College London)Kian Fan Chung(Imperial College London)Peter J. Barnes(Imperial College London)
Abstract
The correlation between exhaled NO and PC20 suggests that exhaled NO or the mechanisms leading to its increase may contribute to airway hyperresponsiveness in asthma. Furthermore, the relationship between sputum eosinophils (%), exhaled NO, and PC20 highlight the potential use of eosinophils (%) in induced sputum and exhaled NO to monitor the severity of asthma.
Asthma and respiratory diseasesChronic Obstructive Pulmonary Disease (COPD) ResearchNeuroscience of respiration and sleepMedicineExhaled nitric oxideMethacholineSputumAsthmaImmunologyBronchial hyperresponsivenessInhalationInternal medicineRespiratory disease
MeSH terms
AdultAsthmaBlood ProteinsBreath TestsBronchial Provocation TestsCross-Sectional StudiesEosinophilsFemaleHumansLeukocyte CountLuminescent MeasurementsLungMaleNitric OxidePredictive Value of Tests
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