article Open AccessTop 1% cited
Prospective Multicenter Study of Viral Etiology and Hospital Length of Stay in Children With Severe Bronchiolitis
Archives of Pediatrics and Adolescent Medicine · 2012 · Vol. 166(8) · pp. 700–700
Jonathan M. Mansbach✉(Boston Children's Hospital)
Abstract
In this multicenter study of children hospitalized with bronchiolitis, RSV was the most common virus detected, but HRV was detected in one-quarter of the children. Since 1 in 3 children had multiple virus infections and HRV was associated with LOS, these data challenge the effectiveness of current RSV-based cohorting practices, the sporadic testing for HRV in bronchiolitis research, and current thinking that the infectious etiology of severe bronchiolitis does not affect short-term outcomes.
Respiratory viral infections researchViral gastroenteritis research and epidemiologyViral Infections and VectorsRhinovirusMedicineBronchiolitisInterquartile rangePediatricsProspective cohort studyOdds ratioEtiologyIncidence (geometry)Acute Bronchiolitis
MeSH terms
BronchiolitisBronchiolitis, ViralFemaleHospitalizationHumansInfantInfant, NewbornLength of StayMaleProspective StudiesRespiratory Syncytial VirusesRhinovirusUnited StatesIncidencePolymerase Chain Reaction
Citations
403
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17.66
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45
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100%
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References
Early-life respiratory viral infections, atopic sensitization, and risk of subsequent development of persistent asthma
Journal of Allergy and Clinical Immunology · 2007 · 740 citations
Rhinovirus illnesses during infancy predict subsequent childhood wheezing
Journal of Allergy and Clinical Immunology · 2005 · 737 citations
Wheezing Rhinovirus Illnesses in Early Life Predict Asthma Development in High-Risk Children
American Journal of Respiratory and Critical Care Medicine · 2008 · 1,298 citations
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