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Genetic and Serologic Properties of Zika Virus Associated with an Epidemic, Yap State, Micronesia, 2007

Emerging infectious diseases · 2008 · Vol. 14(8) · pp. 1232–1239

Robert S. Lanciotti✉(Centers for Disease Control and Prevention)Olga Kosoy(Centers for Disease Control and Prevention)Janeen Laven(Centers for Disease Control and Prevention)Jason O. Velez(Centers for Disease Control and Prevention)Amy J. Lambert(Centers for Disease Control and Prevention)Alison J. Johnson(Centers for Disease Control and Prevention)Stephanie M. Stanfield(Centers for Disease Control and Prevention)Mark R. Duffy(Centers for Disease Control and Prevention)

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Abstract

Zika virus (ZIKV) is a mosquito-borne flavivirus first isolated in Uganda from a sentinel monkey in 1947. Mosquito and sentinel animal surveillance studies have demonstrated that ZIKV is endemic to Africa and Southeast Asia, yet reported human cases are rare, with <10 cases reported in the literature. In June 2007, an epidemic of fever and rash associated with ZIKV was detected in Yap State, Federated States of Micronesia. We report the genetic and serologic properties of the ZIKV associated with this epidemic.

Mosquito-borne diseases and control Viral Infections and Vectors Dengue and Mosquito Control ResearchZika virusVirologySerologyFlavivirusDengue feverBiologyVirusImmunologyAntibody

MeSH terms

Zika Virus InfectionZika VirusAntibodies, ViralBase SequenceDisease OutbreaksHumansImmunoglobulin GImmunoglobulin MMicronesiaPhylogenyRNA, ViralSerologic TestsReverse Transcriptase Polymerase Chain Reaction