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2-Deoxy-D-glucose targeting of glucose metabolism in cancer cells as a potential therapy

Cancer Letters · 2014 · Vol. 355(2) · pp. 176–183
Dongsheng ZhangJuan LiFengzhen WangJun HuShuwei WangYueming Sun
Cancer, Hypoxia, and MetabolismATP Synthase and ATPases ResearchMetabolism, Diabetes, and CancerWarburg effectCancer cellAnaerobic glycolysisCarbohydrate metabolismGlycolysisCancer2-Deoxy-D-glucoseGlucose uptakeCancer researchApoptosis

MeSH terms

AutophagyDeoxyglucoseGlucoseHumansNeoplasmsCell DeathOxidative StressCell Line, TumorMolecular Targeted Therapy
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References
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Cancer Cell · 2008 · 2,271 citations
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Nature reviews. Cancer · 2011 · 3,376 citations
Targeting PI3K/mTOR Signaling in Cancer
Frontiers in Oncology · 2014 · 1,030 citations
Roles of CHOP/GADD153 in endoplasmic reticulum stress
Cell Death and Differentiation · 2003 · 2,809 citations
The Hallmarks of Cancer
Cell · 2000 · 28,385 citations
The Beclin 1 network regulates autophagy and apoptosis
Cell Death and Differentiation · 2011 · 2,468 citations
MYC-Induced Cancer Cell Energy Metabolism and Therapeutic Opportunities
Clinical Cancer Research · 2009 · 964 citations
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