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Alzheimer's Disease Neuroimaging Initiative (ADNI)

Neurology · 2009 · Vol. 74(3) · pp. 201–209

Ronald C. Petersen✉(University of California, Davis)Paul Aisen(University of California, Davis)Laurel Beckett(University of California, Davis)Michael Donohue(University of California, Davis)Anthony Gamst(University of California, Davis)Danielle Harvey(University of California, Davis)Clifford R. Jack(University of California, Davis)William J. Jagust(University of California, Davis)Leslie M. Shaw(University of California, Davis)Arthur W. Toga(University of California, Davis)John Q. Trojanowski(University of California, Davis)Michael W. Weiner(University of California, Davis)

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Abstract

The Alzheimer's Disease Neuroimaging Initiative has successfully recruited cohorts of cognitively normal subjects, subjects with mild cognitive impairment (MCI), and subjects with Alzheimer disease with anticipated baseline characteristics. The 12-month progression rate of MCI was as predicted, and the CSF measures heralded progression of clinical measures over 12 months.

Dementia and Cognitive Impairment Research Health, Environment, Cognitive Aging Alzheimer's disease research and treatmentsNeuroimagingDementiaAlzheimer's diseaseAlzheimer's Disease Neuroimaging InitiativeCognitionDiseaseBiomarkerPsychologyMedicineInternal medicine

MeSH terms

AgedAged, 80 and overAlzheimer DiseaseCross-Sectional StudiesDiagnostic ImagingFemaleFollow-Up StudiesHumansLongitudinal StudiesMaleMiddle AgedBiomarkers