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Highly purified CD44+ prostate cancer cells from xenograft human tumors are enriched in tumorigenic and metastatic progenitor cells

Oncogene · 2006 · Vol. 25(12) · pp. 1696–1708
Lubna PatrawalaTammy CalhounRobin Schneider‐BroussardHeng LiBobby BhatiaShaohua TangJ G ReillyDhyan ChandraJiancheng ZhouKent ClaypoolL. G. CoghlanDean G. Tang
Proteoglycans and glycosaminoglycans researchCancer Cells and MetastasisWnt/β-catenin signaling in development and cancerCD44BiologyProgenitor cellCancer researchCancer stem cellProstate cancerClonogenic assayPopulationStem cellCancer

MeSH terms

AnimalsFlow CytometryHumansMaleNeoplasm MetastasisNeoplasm TransplantationProstatic NeoplasmsStem CellsTransplantation, HeterologousHyaluronan ReceptorsCell Line, TumorCell Proliferation
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References
Prospective identification of tumorigenic breast cancer cells
Proceedings of the National Academy of Sciences · 2003 · 10,327 citations
CD44: From adhesion molecules to signalling regulators
Nature Reviews Molecular Cell Biology · 2003 · 2,338 citations
p63 Is a Prostate Basal Cell Marker and Is Required for Prostate Development
American Journal Of Pathology · 2000 · 608 citations
CD133, a novel marker for human prostatic epithelial stem cells
Journal of Cell Science · 2004 · 763 citations
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