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SIMMAP: Stochastic character mapping of discrete traits on phylogenies

BMC Bioinformatics · 2006 · Vol. 7(1) · pp. 88–88
Jonathan P. Bollback

Abstract

Stochastic character mapping, as implemented in the SIMMAP software, enables users to address questions that require mapping characters onto phylogenies using a probabilistic approach that does not rely on parsimony. Analyses can be performed using a fully Bayesian approach that is not reliant on considering a single topology, set of substitution model parameters, or reconstruction of ancestral states. Uncertainty in these quantities is accommodated by using MCMC samples from their respective posterior distributions.

Genomics and Phylogenetic StudiesGenetic diversity and population structureEvolution and Genetic DynamicsCharacter (mathematics)Character evolutionBayesian probabilitySubstitution (logic)PhylogeneticsMaximum parsimonyBiologyProbabilistic logicEvolutionary biologyMarkov chain Monte Carlo

MeSH terms

AnimalsChromosome MappingComputer SimulationDNA Mutational AnalysisHumansModels, GeneticPhylogenySoftwareStochastic ProcessesUser-Computer InterfaceModels, StatisticalEvolution, MolecularQuantitative Trait Loci

Funding

  • National Science Foundation
  • National Institutes of Health
Citations
952
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References
MacClade 4.0: analysis of phylogeny and character evolution
Choice Reviews Online · 2001 · 5,632 citations
Phylogenies and the Comparative Method
The American Naturalist · 1985 · 10,019 citations
Stochastic Mapping of Morphological Characters
Systematic Biology · 2003 · 928 citations
MRBAYES: Bayesian inference of phylogenetic trees
Bioinformatics · 2001 · 22,042 citations
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