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Biochemical Outcome After Radical Prostatectomy, External Beam Radiation Therapy, or Interstitial Radiation Therapy for Clinically Localized Prostate Cancer

JAMA · 1998 · Vol. 280(11) · pp. 969–969
Anthony V. D’Amico

Abstract

Low-risk patients had estimates of 5-year PSA outcome after treatment with RP, RT, or implant with or without neoadjuvant androgen deprivation that were not statistically different, whereas intermediate- and high-risk patients treated with RP or RT did better then those treated by implant. Prospective randomized trials are needed to verify these findings.

Prostate Cancer Diagnosis and TreatmentProstate Cancer Treatment and ResearchGenital Health and DiseaseMedicineProstate cancerAndrogen deprivation therapyProstatectomyUrologyRadiation therapyHormonal therapyImplantProstate-specific antigenSurgery

MeSH terms

AdenocarcinomaBrachytherapyFollow-Up StudiesHumansMaleNeoplasm StagingProstatectomyProstatic NeoplasmsRadiotherapy DosageRetrospective StudiesMultivariate AnalysisProportional Hazards ModelsSurvival AnalysisChemotherapy, AdjuvantProstate-Specific Antigen
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References
Consensus statement: Guidelines for PSA following radiation therapy1
International Journal of Radiation Oncology*Biology*Physics · 1997 · 1,158 citations
Regression Models and Life-Tables
Journal of the Royal Statistical Society Series B (Statistical Methodology) · 1972 · 38,926 citations
Nonparametric Estimation from Incomplete Observations
Journal of the American Statistical Association · 1958 · 38,793 citations
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