reviewTop 10% cited

ApoE genotype accounts for the vast majority of AD risk and AD pathology

Neurobiology of Aging · 2004 · Vol. 25(5) · pp. 641–650

Jacob Raber✉(Oregon National Primate Research Center)Yadong Huang(Gladstone Institutes)J. Wesson Ashford

Alzheimer's disease research and treatments Computational Drug Discovery Methods Cholinesterase and Neurodegenerative DiseasesApolipoprotein EGenotypeAlleleBiologyDiseaseAlzheimer's diseasePathologyGeneticsMedicineGene

MeSH terms

Age FactorsAlzheimer DiseaseAnimalsApolipoproteins EDisease Models, AnimalGene FrequencyGenotypeHumansMemory DisordersRiskSex FactorsNeurofibrillary TanglesGenetic Predisposition to DiseasePlaque, Amyloid

Funding

National Institutes of Health

Citations

602

FWCI

8.50

field-weighted impact

References

Percentile

98%

vs. same field & year

Citations per year

Cited by

Alzheimer's disease as homeostatic responses to age-related myelin breakdown

Neurobiology of Aging · 2009 · 569 citations

References

Effects of Age, Sex, and Ethnicity on the Association Between Apolipoprotein E Genotype and Alzheimer Disease

JAMA · 1997 · 4,580 citations

Association of apolipoprotein E allele ϵ4 with late‐onset familial and sporadic Alzheimer's disease

Neurology · 1993 · 3,794 citations

The Reliability Theory of Aging and Longevity

Journal of Theoretical Biology · 2001 · 620 citations

Gene Dose of Apolipoprotein E Type 4 Allele and the Risk of Alzheimer's Disease in Late Onset Families

Science · 1993 · 9,373 citations

Apolipoprotein E immunoreactivity in cerebral amyloid deposits and neurofibrillary tangles in Alzheimer's disease and kuru plaque amyloid in Creutzfeldt-Jakob disease

Brain Research · 1991 · 1,150 citations

The Amyloid Hypothesis of Alzheimer's Disease: Progress and Problems on the Road to Therapeutics

Science · 2002 · 13,715 citations

Citation Network

How this paper connects to the literature. Drag to explore, click any node to open that paper.