reviewTop 1% cited

Relationship Between Duration of Untreated Psychosis and Outcome in First-Episode Schizophrenia: A Critical Review and Meta-Analysis

American Journal of Psychiatry · 2005 · Vol. 162(10) · pp. 1785–1804

Diana O. Perkins✉(University of North Carolina at Chapel Hill)Hongbin GuKalina BotevaJeffrey A. Lieberman

Abstract

Duration of untreated psychosis may be a potentially modifiable prognostic factor. Understanding the mechanism by which duration of untreated psychosis influences prognosis may lead to better understanding of the pathophysiology of schizophrenia and to improved treatment strategies.

Schizophrenia research and treatment Mental Health and Psychiatry Obsessive-Compulsive Spectrum DisordersPsychosisPsychopathologyNeurocognitiveSchizophrenia (object-oriented programming)AntipsychoticMeta-analysisPsychologyPathologicalPsychiatryMedicine

MeSH terms

BrainCross-Sectional StudiesData Interpretation, StatisticalFollow-Up StudiesHumansPrognosisProspective StudiesPsychiatric Status Rating ScalesRetrospective StudiesSchizophreniaSeverity of Illness IndexTime FactorsAntipsychotic AgentsTreatment OutcomeOutcome Assessment, Health Care

Citations

1,334

FWCI

25.27

field-weighted impact

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100%

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Cited by

Schizophrenia, “just the facts” 4. Clinical features and conceptualization