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Fatigue in rheumatoid arthritis reflects pain, not disease activity
Lara D. Veeken · 2006 · Vol. 45(7) · pp. 885–889
Abstract
High fatigue levels characterize RA and are mainly linked to pain and depression. The association with disease activity is secondary. Fatigue falls with DMARD and anti-TNF therapy. The balance of evidence suggests that fatigue is centrally mediated in established RA.
Rheumatoid Arthritis Research and TherapiesAutoimmune and Inflammatory Disorders ResearchPeripheral Neuropathies and DisordersMedicineRheumatoid arthritisVisual analogue scaleDepression (economics)Physical therapyInternal medicineSynovitisDiseaseCross-sectional studyQuality of life (healthcare)
MeSH terms
AdultAgedAged, 80 and overArthritis, RheumatoidCross-Sectional StudiesDepressionFatigueFemaleHumansMaleMiddle AgedPainPain MeasurementSeverity of Illness IndexTumor Necrosis Factor-alpha
Citations
445
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7.86
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29
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98%
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References
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Arthritis & Rheumatism · 2003 · 1,756 citations
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The MOS 36-ltem Short-Form Health Survey (SF-36)
Medical Care · 1992 · 29,431 citations
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